From Forbes.com:
The 10 Most Profitable Businesses To Start

No. 1: Accounting Services

Average Pretax Margin: 25%

This industry includes services like bookkeeping, designing accounting systems, payroll billing and preparing financial statements and tax returns. A big yawn–until you see the profits start to pile up. Three reasons: pricing power (everybody needs accountants, no matter how the economy is doing), low overhead and marketing scale, thanks to plenty of repeat clients.

Read more at Forbes.com.